NATURAL HIGH OUR OWN ENDORPHINS

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NATURAL HIGH OUR OWN ENDORPHINS


Are the joys of nature (music, sex, meditation, whatever) as great as drugs? There may be a crumb of truth in this. The brain does produce its own opiates—the enkephalins and endorphins. If we inject these into animals, they cause the same effects as morphine or heroin. The big question is, are they released in circumstances in which we feel great? Can we learn to release them ourselves? 'Ihe latter question is a premise of the science fic­tion book Earth, by David Brin, which depicts a future world where drug abuse no longer exists: the new social outcasts are the brain addicts who have learned to release their own opioids.
Naturally released endorphins do affect behavior. One enterprising sci­entist showed that the release of endorphins went up in animals undergo­ing experimental acupuncture, lending credence to this ancient Chinese healing technique. How can we tell if we are releasing endorphins? First, we could give a drug like naloxone (Narcan) and see if the endorphin high stopped. This approach has actually been tested on people listening to their favorite music, who found that they didn't enjoy the music as much if they were treated with an opiate antagonist (and pleasure is in the ear of the beholder—it has to be music the listener likes, whether it is Bee­thoven or Florence and the Machine). However, playing the music instead of listening to it may be even more effective. A recent study that used increased pain threshold as a surrogate for endorphin activity in the brain showed that playing music or drumming elevated the pain threshold of the musician. How about runner's high? Do endorphins kick in at the end of a marathon? A recent experiment suggests that may happen. Scientists showed that endogenous opioids were released in the brains of people who had just completed a two-hour endurance run. Overall, endogenous opioids play an important role in suppressing pain and in promoting reward. Recent studies showed that animals with no beta-endorphins will not take care of their babies, implicating endor­phins as a critical element in nurturing behavior as well. These neu­rotransmitters are crucial to an important and related group of behaviors essential to human survival. Dynorphins also have an important role to play, telling us that stressful experiences make us feel bad, hopefully teaching us to avoid such experiences in the future.

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