DOING YOUR OWN RESEARCH
If reading this book has raised your level of
interest and you want more specific information, or you want the straight story
about a new development, there is no
substitute for doing your own research.
Reading both scholarly review articles and
original research papers is much
easier than most people believe. In fact, one of the first steps in writing
this book was gathering such research. Much of the library work for the first edition was done by two college
students, neither of whom had any
previous experience using a medical library. Should you decide to investigate for yourself, here are some
suggestions about where to begin.
Public libraries are not likely to have the sorts
of journals and books you will need.
Because there is such a vast amount of medical literature published, most universities with a medical school
have a separate library just to house
all this information. Find a medical library at a nearby medical school. If for some reason you cannot get to a
medical school, check to sec if there
is a college or university biology department nearby and use the
library they use.
Next, go to the library and make friends with the reference librarian, because
you will need his or her help until you are familiar with the library
and the search mechanisms. The most efficient way of searching the
literature is to use MEDLINE or PubMed, databases of the National Library
of Medicine, a US government institution that allows you
search almost all the published medical literature
on any subject you can think of
related to health. You can search by author, title, subject, keyword, institution, and many other descriptors.
In most cases you will find far more information
than you need. A good place to start
is with reviews. Reviews are documents that consolidate and summarize the research and literature
available in a given area, and they
are usually written in less technical language. Reading several recent reviews about the topic you are researching
will help you form a base of knowledge about the subject. Practice using
MEDLINE by starting out with simple
concepts; for example, search for marijuana articles. There are hundreds of them, and many of the titles
will be so technical that they might
seem indecipherable. So tell the computer to select marijuana review articles. This will reduce the number
markedly.
If you have read Buzzed, then you know that one of the active ingredients in marijuana is THC. Try searching for THC
and you will get more articles.
Refine your search by asking for reviews of THC and you will get articles different from those you did when you searched for
marijuana in general. Play with the
database and have fun. Search for all kinds of combinations of keywords, like THC and learning, or
THC and adolescent. You will soon have
an idea of the enormous amount of information there is about just this chemical. Understand, though,
that no one study tells the whole
story.
As a final note, we caution you not to accept everything you
read as directly applicable to the
human condition. Often scientists employ very high levels of a chemical to test for toxic effects in animals, and
sometimes the chemical levels they
use in/on animals are hundreds or thousands of times higher than a human would
ever use, taking into account the weight of the human compared to the animal. Consequently, some of the toxic effects seen in animals may not apply to humans.
On the other hand, animal experiments
cannot reveal many subtle effects of chemicals, particularly psychological ones, and thus animal studies
almost certainly miss some important
effects that humans will experience. So, as you read a scientific paper, remember that it is just a small part of the literature
about a drug, and while the data may
be true, it is
important to understand that data in
the context of everything else known about the drug.