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Alcohol and Drug Problems etiketine sahip kayıtlar gösteriliyor. Tüm kayıtları göster

GETTING CONVICTED: THE PENALTY BOX

26 Temmuz

GETTING CONVICTED: THE PENALTY BOX

The penalty laws of most states and countries are built on a series of leg­islative acts that happened over a long period of time, and thus, they are complicated and not easily summarized. Possession of modest amounts of marijuana can result in a slap on the wrist in some places and serious jail time in others. The same is true for other drugs, although they are usually taken more seriously, even in very small amounts. Often the prosecuting attorney has some leeway about the level of crime with which to charge an individual. The problem is that it is difficult to be sure of (1) the latest changes in the law, (2) the attitude that the prosecu­tor is taking toward drug crimes, and (3) whether that individual will be charged under state or federal statutes. Thus, conviction for the posses­sion of a small, recreational amount of heroin or cocaine could result in either a modest sentence or a huge fine and a long prison term, depend‑
ing on the exact circumstances and the mood of the legal officials over­seeing the case.
It is important to recall that in some states and in the federal system there is structured, or guideline, sentencing. That means that once an individual is convicted of some drug crimes, the sentence is regulated by law and might not be alterable by the judge no matter what the circum­stances. Coupled with the fact that there is no parole in the federal system (and increasingly in the state systems), a conviction can mean long prison time, even if the prosecutor and judge wish it were otherwise.
Here's an example of how things can go terribly wrong as a conse­quence of alcohol, a prescription drug, and harsh laws. One of us (WW) testifies as an expert in legal cases, and a recent one illustrates how the law, the prosecutor, and the courts can interact to ruin the life of an indi­vidual. A man was at a party with his neighbors outside of his home. He consumed a modest amount of alcohol throughout the evening, but at some point he decided to go to bed and took his nightly medicine, which included the sleeping pill zolpidem (generic for Ambien). Before going to bed, he came back to the party but soon appeared intoxicated. He then prepared for bed and went to sleep. Shortly thereafter, he awoke and came out of the house without his shoes, false teeth, or hearing aid, clearly hav­ing just awakened. But he had a gun, which he had retrieved from his bedside where he kept it. He fired twice as he yelled an obscenity to the individuals at the party. No one was hurt. The police were called, and he was arrested.
The man was charged with aggravated assault, and everyone thought he was intoxicated with alcohol. In the law of most states, that is consid­ered "voluntary intoxication" and thus is not a defense against any charges. His defense team argued that he was not intoxicated with alco­hol, but with his prescribed zolpidem, which is known to produce odd behaviors such as sleep driving, sleep sex, sleep shopping, sleep eating, and so forth. If it were the zolpidem, that would be "involuntary intoxica­tion," and that is a defense against such charges.
The jury heard the case and decided that he was intoxicated by alcohol and was therefore guilty. Now, here is where the disaster occurred. In that state, commission of many crimes (such as aggravated assault) with a gun is a mandatory ten-year sentence. If the gun is fired, the mandatory sen­tence is twenty years. In this case the prosecutor chose to charge the man for each of the six people present at the party, and the law requires that the mandatory sentences apply to each charge and be served consecu­tively. This means the man (who has not been sentenced at this writing)
must, by law, be sentenced to 120 years in prison. The judge has no discre­tion in this case.
This is a terrible example of the interaction of intoxication, harsh laws, vigorous prosecution, and finally, the presence of a gun where a sleepy, intoxicated person could access it and fire it. This man had no history of behavior like this and was a decorated soldier. It is very likely that the zolpidem produced the bizarre behavior, but the prosecutor and jury did not see it that way.
The lesson from this is that if a person chooses to intoxicate himself and then commits a crime, that intoxication is usually not a defense against any crime he committed, no matter how impaired he was at the time of the crime.

GETTING CAUGHT

24 Temmuz

GETTING CAUGHT

Most people believe that they will not get caught. Teenagers, in particular, have the feeling that they are "beyond the law" But it does happen. It hap­pens to grandmothers, teenagers, lawyers, doctors, and the most ordinary people on the face of the earth.
Many drug arrests come from the most random events imaginable. In Virginia, an officer stopped a car for having something hanging off the rearview mirror. He became suspicious, legally searched the car, and found major quantities of cocaine. Another drug transporter thought he had the perfect scheme and filled fruit juice cans with cocaine, then resealed them. It is a regular practice for tourists to bring back food from vacation in the Caribbean, and he expected to walk right through customs. What he did not realize was that customs officials knew there was no reason to bring
canned fruit juice from the Caribbean, where it is expensive, to the United States, where it is cheap. He was arrested and convicted for transporting millions of dollars' worth of cocaine.
Even grandmothers are not immune to arrest. A pair of DEA agents working a bus station in North Carolina noticed an elderly woman behav­ing oddly. When they approached her, she moved away and they became suspicious. They conducted a legal search and found a large quantity of cocaine in her luggage.
A college student came back to her dorm room to find the place crawl­ing with campus and city police. While she had absolutely no role in any illegal activity, a friend of her roommate had come to town from another college with a shipment of drugs. Another student, obeying the honor code, had called the campus police. Fortunately, the innocent student was not arrested because the roommate cleared her, but it was a very close call.
The law-enforcement community is actually quite sophisticated in its drug-enforcement efforts. DEA agents work all over the world trying to prevent the transport of drugs into the United States. They have agents working major and minor airports, and even bus stations. The highway patrols of most states have drug interdiction units looking for suspi­cious vehicles. This is not a trivial effort, and it results in so many con­victions that both the state and federal prison populations have grown dramatically.
Yet everyone realizes that most countries are overrun with drugs. It is usually easy to buy the most common illegal drugs in many areas of cit­ies and on college campuses. So why is the legal interdiction effort per­ceived as failing? It is not exactly failing, but rather it is being overwhelmed. Many, many people are caught in the legal system, but there is always someone else to replace each person caught. Routine usage of cocaine, crack, or heroin can be a very expensive habit, and the only way that most people can maintain such expensive behavior is to turn to dealing. As we say elsewhere in this book, cocaine and opiates can be extremely reinforcing, and they are also expensive in the quanti­ties that habitual users consume. The combination of dependence and expense often leads users to become dealers until they are stopped by medical intervention, arrest, or death.
What does this have to do with the average reader of this book? Any­one who can read this book no doubt has the ability to do honest and legal work and have a successful life. Such a reader might feel that she is above being caught, or just not in the "wrong" circle of friends. This
naiveté might be the most dangerous attitude of all, because, like most jobs, illegal drug dealing depends on knowledge, skills, and having a network of people. Most casual dealers do not have the knowledge or, fortunately, are not willing to do what is necessary to involve themselves fully in the drug culture. Thus, they approach the whole issue as ama­teurs, and like many amateurs in anything, they fail miserably. Only in this case, the stakes are much higher. They can get caught, lose a lot of
money, become victims of criminal violence, or become heavily depen­dent on the substance they are dealing.
As we all know, some people think they have few opportunities and only a short time to live. They will deal drugs no matter what anyone says. In their lives they see jail time as just the cost of doing business. However, a district attorney who has prosecuted thousands of drug cases had just one bit of advice: people with families, an opportunity for education, and a supportive network of friends have so much to lose from being on the wrong side of the legal system that they should never become involved with it. A felony conviction can strip a person of so many opportunities in this society and can cost families so much in
pain, suffering, and financial loss that no amount of money or drug experience is worth the risk.

HOW CAFFEINE MOVES THROUGH THE BODY

01 Haziran
HOW CAFFEINE MOVES THROUGH THE BODY
CAFFEINE



Caffeine is almost always taken by mouth, and so it is absorbed into the blood primarily through the linings of the stomach, small intestine, and large intestine. It is only slowly absorbed through the stomach, and so most absorption occurs at the next step along the gastrointestinal tract, the small intestine. However, once it reaches the intestines, virtually all of the caffeine that was ingested is absorbed. A given oral dose of caffeine takes full effect within thirty to sixty minutes, depending upon how much food is in the stomach and intestines and how concentrated the caf­feine is in the substance that contains it.
Caffeine is evenly distributed throughout the body, metabolized by the liver, and its breakdown products are excreted through the kidneys. The body eliminates it rather slowly, with the half-life of a given dose of caf­feine being approximately three hours. Thus, some of the caffeine that one consumes in the morning is still around well into the afternoon. A person who drinks several cups of coffee or caffeinated sodas across a morning or afternoon is adding on to an existing load of caffeine with each subse­quent drink and may end up feeling rather jittery by the end of the day.

HOW CAFFEINE WORKS
Caffeine is the best known of a class of compounds called xanthines (pro­nounced "zan-theenez"). Theophylline, another xanthine found in tea, is prescribed for breathing problems because it relaxes and opens breathing passages. However, there is so little of it in brewed tea that it exerts no significant stimulant effects in that form. In addition to a small amount of caffeine, chocolate contains theobromine, another xanthine, but one with far less potency than caffeine.
All the xanthines, including caffeine, have multiple actions. The major action is to block the action of a neurotransmitter/neuromodulator called adenosine, which is in the brain (more on this in the following). There are also adenosine receptors throughout the body, including those in blood vessels, fat cells, the heart, the kidneys, and many types of smooth mus­cle. These multiple actions create a confusing picture because the direct effects of caffeine on a system can be enhanced or suppressed by indirect effects on other systems.

EFFECTS ON THE BRAIN
Adenosine receptors, the main site of caffeine action, cause sedation when adenosine binds to them. Adenosine, a by-product of cellular metabolism, leaks out of cells. So, as neurons become more active, they produce more adenosine, and this provides a "brake" on all the neural activity—an ingenious self-regulation by the brain. Caffeine thus produces activation of brain activity by reducing the ability of adenosine to do As job. This is a good example of how a drug can produce an effect (in this case, central nervous system iCNSI stimulation) by inhibiting the action of a neu­rotransmitter that produces an inhibiting effect (a positive coming from two negatives). At moderate doses of around 200 milligrams (about what you get from one to two cups of strong coffee), electroencephalograph (EEG) studies indicate that the brain is aroused. Higher doses, in the range of 500 milligrams, increase heart rate and breathing. Activation of these centers also causes a constriction, or narrowing, of blood vessels in the brain (though outside the brain caffeine has a direct effect on blood vessels that does just the opposite—dilating, or widening, them).
Caffeine also lowers the amount of blood flow within the brain. It seems strange at first that a drug with such strong stimulant effects in the brain would actually decrease blood flow within the brain. But studies have shown that a dose of 250 milligrams (about what you get from two to three cups of coffee) reduces blood flow by nearly one-fourth in the gray matter of the brain (made up mostly of nerve cells) and by about one-fifth in the white matter through which fibers connect groups of nerve cells
into functioning circuits. The fact that caffeine has such powerful stimulant effects despite its decrease of cerebral blood flow underscores how powerful its stimulant effects really are. Further, the effects of a single dose of caffeine on cerebral blood flow were the same in heavy caffeine users and in light users, indicating that the blood flow effect is not one to
which people become tolerant.
People may develop a mild tolerance to some of the effects of caffeine, but most tolerant people can achieve an arousing effect by increasing the dose. The tolerance that develops to the brain-arousing effects of caffeine is less severe than the tolerance that develops to some of its effects on other parts of the body (see the following).

Dependence on caffeine can develop as well, as indicated by the occur­rence of withdrawal symptoms when caffeine intake is abruptly stopped. Between twelve and twenty-four hours after the last dose of caffeine, users generally experience headaches and fatigue that may persist for several days to a week but that are usually strongest during the first two days after quitting. Nonprescription pain relievers such as acetaminophen (Tylenol) or ibuprofen relieve the headaches, and moderate doses can be taken throughout the withdrawal period—just be careful to avoid taking pain medications that include caffeine Many people have found that they enjoy, and indeed rely on, the psy­chological effects of caffeine. While this wouldn't meet our definition of addiction, most caffeine users find the effects pleasant enough to continue using this drug. Therefore, those who decide to quit should also be pre­pared to give up those caffeine-aided feelings of alertness and mild eupho­ria, which may have become a very regular and important part of each day. A related issue is that people who drink caffeinated beverages often do so at the same or similar times of day. In that way the drinking itself may become a part of important daily rituals. It is important to anticipate that changing those rituals may be difficult as well.

IS THERE A DEFICIENT BRAIN CHEMISTRY IN ADDICTS?

20 Mayıs
IS THERE A DEFICIENT BRAIN CHEMISTRY IN ADDICTS?
CHEMISTRY IN ADDICTS


If everyone with a brain can become an addict, why are there (relatively) so few addicts? Could there be a unique group of people whose pleasure circuits are abnormal in some way so that these drugs feel particularly good? Or could there be a group of people whose pleasure circuits don't work very well, so that they are inclined to drink alcohol, smoke, or take cocaine to feel normal? There are probably people in each of these catego­ries. In studying these questions in human addicts, there is a real "chicken and egg" problem. If brain function is abnormal, it is impossible to know whether the abnormality was caused by years of substance abuse or was present before. This is one challenge about the aforementioned dopamine receptor finding. Some scientists have tried to solve this problem by studying the children of alcoholics. There are certain EEG (brain wave) changes that have been noted in some alcoholics and in their sons. How­ever, we don't really understand the significance of this EEG anomaly yet. The only way to be sure is to study these children until they become adults to see if this difference predicted alcoholism. Such studies are underway, but they take a long time. We can do these experiments in animals, and we have found that even with free access to cocaine, only a certain per­centage of animals (about a fifth) progress to the stage of compulsive use. Are these differences due to a deficient gene that could simply be repaired? The mapping of the human genome has really speeded up the search for genes related to addiction as well as other diseases. Many candi­dates have been identified. Some are specific to specific addictions. A vari­ant of one gene for the receptor through which ethanol acts is associated with alcoholism, and a variant for a receptor that narcotics act upon is associated with narcotic addiction. Others, like the dopamine D2 receptor, are related to all addictions. Others have been surprises. One of the best
genetic "predictors' of nicotine dependence is a gene that controls the breakdown of nicotine in the liver—not anything related to brain function at all. Finally, there are genes that seem to protect people from addictions.
Two genes involved in alcohol degradation fit into this category (see the
chapter on alcohol). So, as many scientists predicted, drug addiction is a complicated disorder that can involve many genes. Can we fix the affected genes? Not yet. Do we want to? Because most or these genes affect normal brain activities, we are not even vaguely close to knowing if changing them would treat addiction without causing other troubles. And even if we
could, the ethical questions raised by such manipulations are huge. Finally, it is important to realize that biology is not destiny. People are more than bags of genes that produce behavior. They are influenced bytheir environment and can control their behavior voluntarily. Simply possessing a particular gene that has been found in the brains of some alco‑ holics does not mean that an individual must become an alcoholic. If he or she abstains from alcohol, for one thing, there will never be a problem.


Maybe these slightly abnormal genes provide some benefit to the person that we don't fully understand. On the other hand, people with no genetic predisposition may experience such traumatic life circumstances (being sexually abused during childhood, for example) that they develop com­pulsive use of alcohol or other substances in an attempt to self-medicate their psychological trauma. The bottom line is that everyone with a brain can become an addict. Given the diversity of human brains, it is likely that some people will find the experience more compelling than others, but we have not really defined exactly what brain chemistry leads to this vulnerability yet.

Drug Addiction

12 Mayıs
Drug Addiction

THE DRAMA of drug addiction is obvious. It fills the stage with violence, stealing, arrests, intense emotional highs, periods of des-perate craving, and possible death from overdose. Less obvious, however, is the stability that actually underlies these fluctuations—a stability that includes both the addict and his family. These phenom-ena are stable in their predictability, their repetitiveness, and in the function they serve for the people involved. This chapter is an attempt to identify some of the elements within the process and integrate them into a conceptual model.
Our plan is to lead the reader through the evolution of some ideas that have emerged from our observations and research, and to integrate these, whenever possible, with the work of other investi-gators. The focus will be on a class of factors that have not always been considered in the drug-abuse field and appear to be quite potent, especially as they relate to the maintenance of addiction. We wish to emphasize that, although we are applying a particular framework to compulsive drug use, we are not denying the importance of physio-logical variables in addiction; we recognize that a drug can be ex-tremely powerful in its own right. It is also accepted that—in addition to the family—economic, environmental, and conditioning determi-nants are also crucial.
This chapter is a revision of a paper by the authors entitled "Heroin Addiction as a Family Phenomenon: A New Conceptual Model- and is reprinted with per-mission from the American Journal of Drug and Alcohol Abuse, 1978, 5, 125-150. 0 Marcel Dekker, Inc.

Appreciation is extended to Jim Mintz, PhD, Salvador Minuchin, MD, Braulio Montalvo, MA, and Bernice I.. Rosman, PhD, for their helpful comments on an earlier version of this chapter.
RESEARCH ON ADDICTS' FAMILIES

Drug abuse generally has its origins in adolescence. It is tied to the normal, albeit troublesome, process of growing up, experimenting with new behaviors, becoming self-assertive, developing close (usually heterosexual) relationships with people outside the family, and leav-ing home. Kandel et al.,76 extrapolating from their data, propose that there are three stages in adolescent drug use and each has different concomitants. The first is the use of legal drugs, such as alcohol, and is mainly a social phenomenon. The second involves use of marijuana and is 'also primarily peer-influenced. The third stage, frequent use of other illegal drugs, appears contingent more on the quality of parent-adolescent relationships than on other factors. Thus, it is concluded that more serious drug abuse is predominantly a family phenomenon, which corresponds to the conclusion by Blum et al." that the peer group has little or no influence as long as the family remains strong.
At least five literature reviews have been published that deal with family factors in drug addiction.n7. 8". "7 "I• ''" These reviews describe a prototypic pattern for male addicts' families in which the mother is involved in an indulgent, enmeshed, overprotective, overly permissive relationship with the addict, who is put in the position of a favored child. Often he is -spoiled.-P's He is reported by the mother
to have been the -easiest to raise- of the children and was generally good- as a child.s1 L') Fathers of male addicts are reported to be detached, uninvolved, weak, or absent.* Compared with normals, the father-son relationships in addicts' families are described by the addict as being quite negative, with harsh and inconsistent discipline, especially for those who inject heroin versus those who inhale it.'t•"'"
A disproportionate number of fathers are reported to have a drinking problem."3,58.105,                 ""' 179'1"St Schwartzman' 3" describes two types of addict fathers, a -straw man- type who is authoritarian, violent, but easily controlled by mother, and a distant type who is clearly secondary to mother in terms of power within the family. Interestingly,
*As noted in Chapter 6, caution should be exercised regarding these conclusions, as Kaufman and Kaufmann" noted enmeshed father-child relationships in 40%, of their cases—particularly within certain ethnic groups. Further, Alexander and Dibb2 feel the father (rather than the mother) assumes the overinvolved role in some middle-class families, a pattern we also found in approximately 5% of the Addicts and Families Program (AFP) families.
10f course the statistical distributions in these and other studies cited in this section are overlapping (e.g., some -normal" families vvill also show such patterns).
Rosenberg123 reports that siblings of male addicts are more likely to have a positive relationship with the father. In contrast to males, female addicts seem to be in overt competition with their mothers (whom they see as overprotective and authoritarian), while their fathers have been reported to be inept, indulgent of them, sexually aggressive, and often alcoholic; the probability of incest is much greater than normal:6.'4, '9" with estimates running as high as 90%.'8 A high incidence of parental deprivation is reported for families of both sexes, many of whom have experienced separation or death of a
parent—most commonly father—before age 16.', li,67,80 /,,12(.182 How_
ever, this incidence appears to be changing in recent years, so that rates in addicts' families are now more comparable to the overall population.'51 In general, research in this area has progressed from reports by the user about his family, to dyadic (e.g., mother-child) assessments, to triadic (parents and child) concepts, and, with the more sophisticated studies, to assessments of the interactional behavior of the whole family. 

ADDICT FAMILY CONTACT
One area that has tended to be overlooked or unrecognized in the drug-abuse field is the extent to which -hard- drug users are involved and in contact with the people who raised them. For adolescents such involvement is natural and developmentally appropriate, since they are still minors and are generally not expected to have left home. On the other hand, it is not necessarily obvious that addicts in their late 20s and early 30s would still be involved with their families of origin. Their age, submersion in the drug subculture, frequent changes in residence, possible military service, and so forth, would seem to imply that they are cut off, or at least distanced, from one or both parents.
On the other hand, there is a preponde
rance of evidence (pre-sented in Appendix A) that, despite their protestations of indepen-dence, the majority of addicts maintain close family ties. Even if they do not reside with their parents, they may live nearby, and their frequency of contact is much higher than that occurring among comparable -normals,- other psychiatric patient groups, or even polydrug abusers. Fifteen of 17 reports on living arrangements, and 7 of 7 reports on frequency of family contact attest to this pattern (these studies are reviewed in Appendix A). For example, Perzel and Lamon"3 found that 64%, of heroin addicts were in daily telephone contact with at least one parent, compared to 51% of polydrug
abusers and 9% of normals. Further, this appears to be an inter-national phenomenon, as similar rates of addicts living with parents have been found in Puerto Rico, Italy, England, and Thailand, in addition to North America. In sum, it would appear that at least two-thirds of male hard drug users under age 35 live with the people that raised them and 80-85% are in at least weekly contact with these same parental figures. In fact, we have observed these intense en-tanglements so often in our clinical work that we are by now skeptical when any addict tells us that he does not see his parents regularly. We tend to regard such responses as moves to protect the family rather than as valid in their own right (see Chapters 4 and 5 ).
Of course, either living with parents or seeing them regularly is not necessarily' an indication of dysfunction. Depending on the cul-tural and ethnic milieu, such arrangements can be quite natural, and maintaining regular family involvement certainly does not mean one will become a drug addict. What may be more important is the quality and the operational—functional structure within families who develop drug-abusing offspring, with consideration also given to their stage in the family life cycle. Overinvolvement, then, can only be considered an indirect measure of family dysfunction. However, there is some evidence that it can have meaning and value in terms of determining both the prognosis for existent treatment paradigms and the direc-tion for new therapeutic modes. For example, Vaillant182 found that addicts who became abstinent did not live with their parents, and Zahn and Ball's '96 data indicate that cure was associated with not living with parents or relatives. Both reports noted a correlation between living in the home of relatives and continued addiction. Further, in a comparison of posttreatment outcomes by Stanton et significant correlations were found between regularity of con-tact with a parent and the extent of use of illegal drugs (.20), as well as use of marijuana (.23); the correlations were similar when mea-sured against whether the addict lived with his parents (all illegal drugs, .21; marijuana, .22). These results imply that being closely involved with one's family of origin is not necessarily healthy, especially among young men aged 20 to 35

DUNCAN STANTON - THOMAS C. TODD

Acohol Dependence

10 Mayıs
Acohol Dependence

It is important to distinguish between alcohol dependence and alcohol abuse. Generally, alcohol abuse refers to patterns of drinking that give rise to health problems, social problems, or both. Alcohol dependence (often called alcoholism) refers to a disease that is characterized by abnormal seeking and consumption of alcohol that leads to a lack of control over drinking. Dependent individuals often appear to crave alcohol. They seem driven to drink even though they know that their drinking is causing problems for them. The signs of physical depen­dence begin within hours after an individual stops drinking. They include anxiety, tremors (shaking), sleep disturbances, and, in more extreme cases, hallucinations and seizures. Until a chronic drinker actually stops drinking, it is quite difficult to make a definitive assess­ment of alcohol dependence. But for most practical purposes, this for­mal diagnosis is unnecessary, because the social and medical problems that most alcoholics experience should be recognizable to health profes­sionals. See the section "How to Spot a Problem Drinker" on page 55 for some general guidelines.
PRENATAL EXPOSURE
Acohol Dependence

The dangers of prenatal alcohol exposure have been noted since the time of Aristotle in ancient Greece. However, it was not until 1968 that formal reports began to emerge. The early studies of fetal alcohol syndrome (FAS) described gross physical deformities and profound mental retarda­tion among children of heavy-drinking alcoholic mothers. Although this was a very important set of findings, at first there was no evidence that women who drank more moderately were placing their children at risk. In fact, for many years, pregnant women were often encouraged to have a glass of wine with dinner or take a drink now and then during pregnancy to help them fall asleep or just to relax.
It took a while for the effects of moderate prenatal drinking to be noticed, because the children have none of the very obvious defects asso­ciated with the full-blown fetal alcohol syndrome. However, it is now clear that there is a less severe, but very well documented, pattern of defi­cits associated with more moderate prenatal drinking—a pattern described as fetal alcohol effects (FAE). School-age children with FAS or FAE are frequently described as hyperactive, distractible, and impulsive, with short attention spans—behaviors similar to those observed in chil­dren with attention deficit disorder (ADD). However, the FAS and FAR children differ from ADD children in that they are more intellectually


impaired. In recent years the term fetal alcohol spectrum disorders (FASD) has emerged as an umbrella term to include the full range of neurological, cognitive, behavioral, and learning disabilities associated with prenatal alcohol exposure.
The impairments of intelligence and behavior in people with FASD appear to persist into adulthood and are probably lifelong, resulting in IQ scores markedly below average, often well into the moderately retarded range. Those with PAS scored worse than those with RAE, but both were significantly below normal, hampered in reading and spell­ing and most profoundly deficient in mathematical skills. More import­ant, the FAE patients did not perform any better than the FAS patients on academic achievement tests, though their IQs were somewhat higher. What all this means is that even moderate drinking during pregnancy can create permanent intellectual disabilities. Some studies using animal models of FAE even suggest that just one drink per day impairs the function of brain areas related to learning in the adult offspring.

The bottom line is that there is no identified safe level of drinking during pregnancy. The smart decision for a woman is simply not to drink if she is pregnant or thinks that she might be.